Food and Its Impact on Type2 Diabetes

diabetes-Obesity is a challenging problem in modern world especially in developing countries. Obese people are vulnerable to different health conditions including for instance heart disease and type2 diabetes. The more weight you gain, the more risky it becomes to increase blood sugar levels in the body.

It’s known that nutrition has a direct effect on one’s weight. When the calories you consume in your food and drinks are over than what your body needs, you start gaining weight. But gaining more weight makes you at risk of type2 diabetes. So, what type of food that raises the chances to becoming obese and help body improve the disease?

A recently published study led by researchers from Department of Food Science and Nutrition, Women’s University, Mumbai, India has investigated the impact of certain types of food on weight gaining and metabolic response.

In order to “classify food according to their hyperglycemic quality, glycemic response to equi-quantity of commonly consumed carbohydrate,” researchers compared rich foods including “biscuit, Chapatti, Puffed rice, Potato, and least for Rice…with that of white bread (reference) in healthy volunteers.” Then “the Blood glucose response to 100g of the test foods were compared with an equal quantity of standard food—White bread.”

To have an idea of the glycemic response, it is response to a food or meal is the effect that food or meal has on blood sugar (glucose) levels after consumption.

Researchers made significant notices. They noted that 100g of rice “would be expected to induce a higher glycemic response, but its response is equivalent to that induced by 20g bread only; much lower than that of biscuit and chapatti”.

Also, they noted that “100g Marie biscuit induced significantly higher glycemic response than the same amount of bread (p<0.01), rice (p<0.01), puffed rice (p<0.01) and potato (p<0.01).” Researchers stated that “weight ratio such as biscuit and puffed rice, have light and porous nature and are generally consumed in lesser quantities at one time. But most often, doctors and nutritionist encourage the consumption of these snacks to patients for their apparent lightness.”

For chapatti which is “prepared from whole wheat flour has been given preference over white rice” researchers noted “that the predicted glycemic response to regular serving size of chapatti (30g) is much higher than that of rice”.

On the light of this study’ results, there are certain foods that can increase the risk of improving diabetes than others. Healthy foods especially those rich vitamins are important in reducing susceptibility to improving type2 diabetes.

A study which is published in Journal of Research in Diabetes found that “deficient levels of vitamin D may predispose euglycemic person for diabetes and dyslipidemia. Vitamin D supplements in euglycemic individuals may play an important role in reducing the risk.”

What you eat has a direct impact on your health including sugar levels in blood, something that can affect your improvement of diabetes. The type of food you eat is important, but also the amount matters. For a healthy living, one should consider what he consumes including quantity and quality.

 

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What Relation Between Serum Alanine Transaminases and Type 2 Diabetes?

Diabetes

 

Liver is an important element for digestive system in particular and body in general with multiple functions including production of biochemicals, detoxification, among other roles. Also liver is vital for blood considering the decomposition of red blood cells, plasma protein synthesis, as well as its functionality in relation with different diseases that touch blood such as type 2 diabetes.

When liver is injured or suffering certain damages, the alanine transaminase (ALT) is found in the body. ALT is an enzyme produced by liver cells and its role is helping the body metabolize proteins. The founding of ALT in the serum is an indicator of tissue injury, and insulin resistance, something that leads to type 2 diabates.

But what kind of relation that may be found between type 2 diabetes and Alanine Transaminases? This what has been subject to a new study which is carried by a group of researchers from Department of Biochemistry, Government Medical College Aurangabad, Maharashtra India.

Type 2 Diabetes is scientifically defined as a metabolic disorder because of relative deficiency of insulin, something that leads to disorder in carbohydrate, lipid and protein metabolism. And in type 2 diabetes, liver plays an important role in carbohydrate homeostasis and maintaining level of glucose in blood.

In quest of answers, the study “investigated 90 cases of T2DM for liver enzyme ALT, lipid profile.” Researchers took blood samples from the participants after an overnight fasting, then “assayed for serum ALT, cholesterol, triglycerides, and low and high density lipoproteins.” Results showed that “serum ALT levels were raised significantly among 36 (40%) cases of T2DM in studied group.”

Researchers said that “significant positive association of ALT was observed between BMI and W: H (r= 0.401, 0.532) and serum TG, LDL (r= 0.431, 0.555) levels. Significant negative association was observed between ALT and HDL (r=-0.072) among cases. Our findings suggest marked risk of developing liver and cardiovascular disease due to elevated ALT and atherogenic lipoprotein profile in patients with T2DM.”

To compare with other studies that have  “linked association of ALT with insulin resistance, metabolic syndrome and T2DM”, researchers said that the study findings are in consistence with those of Adeniran Samuel Atiba et al that was published in 2013. Also, this study’s results are “in agreement with Idris et al (2011), Nannipieri N et al (2005) confirming the role of insulin resistance in pathophysiology of liver diseases.”

Researchers summed up that the “serum ALT, a surrogate marker of liver damage is elevated with dyslipidemia in the patients of T2DM.” But, they stressed out that “early detection of liver abnormality and intervention will help to prevent further progression to liver cirrhosis and chronic liver disease.”